Patented Technology

One-of-a-kind bioelectric technology

Microcell Batteries

V.Dox™ Technology employs a matrix of embedded microcell batteries comprised of elemental silver and elemental zinc. When in direct contact with a conductive medium, chemical reactions occur involving the transfer of electrons from the zinc to the silver in a process known as oxidation-reduction or REDOX reaction.⁶ This generates an electric field on the dressing surface.

Conductive Medium

A conductive medium is any solution that permits the flow of electrons. Examples of highly conductive media are saline solution, hydrogels, and certain serums. Due to the high concentration of naturally occurring salt ions in the human body, bodily fluids such as sweat and wound exudate are also conductive media capable of activating V.Dox Technology’s microcell batteries.⁷

Electricity

V.Dox Technology generates electricity designed to mimic the skin’s physiologic electrical energy and may reduce the risk of infection^2-5 while supporting the body’s natural healing process.⁶

Inspired by the Body

Electricity is Essential to Healing

The body naturally creates and uses electrical energy to promote healing.¹

Physiologic Electrical activity in the Skin

Intact Skin

Electric fields exist naturally in the skin, creating surface energy potential known as transepithelial potential (TEP).^8-9,11

Wounded Skin

When skin is wounded, a change in electric potential occurs. These physiologic changes are essential to cell migration and wound healing.¹⁰

V.DOX Technology

V.Dox Technology is designed to mimic the skin’s physiologic electrical activity, harnessing the power of electricity to reduce the risk of infection while supporting the body’s natural healing process.

Inspired by the Body

Electricity is Essential to Healing

The body naturally creates and uses electrical energy to promote healing.¹

Physiologic Electrical activity in the Skin

Employing a patented matrix of embedded microcell batteries, V.Dox Technology wirelessly generates an electric field in the presence of a conductive medium.

Microcell Batteries

Moisture-activated microcell batteries comprised of elemental silver and elemental zinc are embedded in a substrate.
Upon moisture activation, chemical reactions between the silver and zinc occur, involving the transfer of electrons from the zinc to the silver in a process known as oxidation-reduction or REDOX reaction, which wirelessly generates an electric field.

Energized by Results

Optimizing Outcomes

Wound bioburden is associated with delayed healing and increases the chance for infectious complications.¹⁴ Independent, peer-reviewed, published, and standardized laboratory studies and data on file^2-5 demonstrate that Vomaris’s antimicrobial wound dressing kills a broad-spectrum of harmful pathogens, including multi-drug resistant⁴ and biofilm-forming bacteria.^2,5 This may reduce the risk of infection while supporting the body’s natural healing process:

• Sustained broad-spectrum antimicrobial impact for up to seven days,³

• Bactericidal against gram-positive and gram-negative pathogens,⁴

• Electric field-induced antimicrobial impact.²

Prevention of Bacterial Growth

V.Dox Technology

Silver Only

Placebo

In vitro study of dressings embedded in agar demonstrates effectiveness against A. baumannii bacteria absence of bacterial growth above Vomaris’s antimicrobial dressing (see V.Dox Technology picture), compared to diffuse bacterial growth above the silver and placebo control dressings at 24 hours.²

Antimicrobial Impact on Biofilm-Forming Bacteria

V.Dox Technology

Silver Only

Placebo

Live/dead fluorescence staining demonstrates killing of biofilm-forming P. aeruginosa bacteria within Vomaris’s antimicrobial dressing (see V.Dox Technology picture), compared to silver and placebo control dressings at 24 hours.²

Red=Dead Green=Alive

Energized by Results

Improvement in rate of epithelialization vs. standard of care. Prospective case series; Skin Graft Donor Site Study (N=13).¹²

K-120 Rev. B – Last updated: February 2023